Mrs. Mahoney is co-founder and co-chairman of the Harvard Mahoney Neuroscience Institute and a trustee of the Dana-Farber Cancer Institute in Boston, MA; a director of Charles A. Dana Foundation and a former director of The Mahoney Institute of Neurological Sciences at University of Pennsylvania. Mrs. Mahoney serves on the honorary board of The Boys Club of New York and on the national board of The Boys & Girls Clubs of America. In Palm Beach, she is a member of the board of Hospice of Palm Beach County Foundation and The Preservation Foundation. Mrs. Mahoney has been honored by The American Ireland Fund and The Boys Club of New York; received the Bronze Keystone Award from the Boys & Girls Clubs of America; the Woman of Distinction Award from Birmingham Southern College and Palm Beach Atlantic University. In 2015 she was the recipient of the Ellis Island Medal of Honor. She has honorary degrees from Birmingham Southern College in Birmingham, AL, and Sacred Heart University in Fairfield, CT.

She was the executive producer of a documentary entitled Journey Interrupted in 2008 and wrote a book by the same title in 2016 about her years in Japan during WWII. A motion picture based on her book is currently in production. Mrs. Mahoney is the mother of two boys and a stepdaughter, has nine grandchildren, and five great-grandchildren. She has lived in Palm Beach since 1980 and has summered in Switzerland for the past twenty-seven years. She is now a full-time resident of Palm Beach!